Association of deprivation on outcomes in people with chronic kidney disease (CKD)
In a recent study by Al-Chalabi, 2024 the association of CKD with deprivation was investigated.
Why is this important?
Due to the high correlation of chronic kidney disease (CKD) with other comorbidities (e.g. diabetes/obesity), the effect of CKD on deprived people is not clear. This study aimed to examine whether deprivation was associated with adverse outcomes in patients with CKD, independent of cardiometabolic morbidities.
What did the study show?
This is a retrospective study of patients with non-dialysis-dependent CKD (ND-CKD) as part of the Salford Kidney Study.
It found that people living in the least deprived areas (n = 319) had a lower risk of combined outcomes (all-cause mortality and renal replacement therapy) when compared with the most deprived group (n = 813). This effect persisted even when adjusted for other comorbidities.
Also areas with lower scores for education, income and employment were significantly associated with a higher risk.
Conclusions. This study has identified that in people with ND-CKD, unemployment, poor educational attainment and lower household income were associated with poor outcomes. The association of deprivation with adverse outcomes persisted despite adjustment for cardiometabolic morbidities.
How does this affect you?
If you are in that patient group, you should both be aware of a higher tendency for CKD; and seek screening from your GP, and early intervention (e.g. a focus on other risk factors (e.g. weight loss, and possible treatment with ACE/ARB/SGLT2i) if indicated.
Summary poster
Last Reviewed on 13 July 2024
