What is analgesic nephropathy? In this article we will describe what is analgesic nephropathy. It is a condition characterised by damage to the kidneys due to long-term or excessive use of certain pain medications; particularly analgesics like nonsteroidal anti-inflammatory drugs (NSAIDs) and combination analgesics containing phenacetin, aspirin, or acetaminophen. Note. NSAIDs can affect the kidneys […]
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What is IgG4-related disease (IgG4-RD)? Key points about IgG4-RD and kidneys. So. What is IgG4-related disease (IgG4-RD)? IgG4-related disease (IgG4-RD), a recently recognised systemic inflammatory disorder, generally presents as a mass-forming lesion, or lesions, or organ enlargement It is characterised by tissue infiltration with lymphocytes and IgG4-secreting plasma cells (IgG4+PC), various degrees of fibrosis (scarring)
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What are the 5 stages of diabetic nephropathy (and treatments)? There are 5 stages of diabetic nephropathy (DN). This is called the Mogensen classification of diabetic nephropathy. DN Stage 1. Hyperfiltration Years from diagnosis – at onset Urinary dipstick – negative uACR (lab urine test) – normal, i.e. < 3 mg/mmol GFR – increased (>150
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Gitelman Syndrome – overview Gitelman syndrome (GS) is an inherited (autosomal recessive) salt-losing kidney disease characterised by: Increased potassium loss in the urine Hypokalaemia and hypomagnesaemia = low potassium and magnesium (both electrolytes/minerals)in the blood Alkalosis = too much alkali in the blood Hypocalciuria = not enough calcium in the urine. The abnormality is in
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Retroperitoneal fibrosis (RPF) – overview Retroperitoneal fibrosis (RPF) is a rare condition in which there is fibrous tissue (scarring) in the retroperitoneal space, which is located behind the abdomen (tummy), in front of the spine. Here is an overview of retroperitoneal fibrosis. 1. Definition In retroperitoneal fibrosis the scar tissue in the retroperitoneum can compress
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What is medullary sponge kidney (MSK)? Medullary sponge kidney (MSK) is a congenital disorder, meaning it is present at birth. MSK occurs when small cysts (sacs) full of fluid form within the inner area (called the medulla) of the kidneys. It is also called Cacchi-Ricci Disease. In 70% of patients small stones form within the
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Causes of kidney disease list This is a list of diseases of the kidney and urinary tract, both common and rare, for patients and renal health professionals. Many can cause chronic kidney disease (CKD). Please feel free to contact us, if you think we have left any out. Abderhalden–Kaufmann–Lignac syndrome (Nephropathic Cystinosis) Abdominal Compartment Syndrome
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Alport Syndrome Alport Syndrome is a rare inherited disease that can cause kidney failure, deafness and eye abnormalities (Alport UK). It can lead to the need for dialysis and/or a kidney transplant when people are in their 20s and 30s. The average age of commencing dialysis in X-linked Alports syndrome is about 35 years. Even
What is rapidly progressive glomerulonephritis? Rapidly progressive glomerulonephritis (RPGN) is one of the 7 types of chronic glomerulonephritis (GN). They are all ‘autoimmune diseases’ where the immune (defence) system attacks normal tissue in the kidney (including the glomeruli). Why and how they occur is unclear. RPGN is not caused by a single disease. It has
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What is post-infectious glomerulonephritis? Post-infectious glomerulonephritis (PIGN) is one of the 7 types of chronic glomerulonephritis (GN). They are all ‘autoimmune diseases’ where the immune (defence) system attacks normal tissue in the kidney (including the glomeruli). Why and how they occur is unclear. So. What is post-infectious glomerulonephritis? PIGN normally develops rapidly, and (classically) follows
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