Dr Andy Stein, Author at Chronic Kidney Disease Explained

Eight year old girl receives kidney transplant from mother without immunouppression

Uncategorised / 22 September 2023

Aditi with her mother and father Eight-year-old Aditi Shankar has become the first child in the UK to receive a special type of kidney transplant that does not require her to take long-term drugs to stop organ rejection. Doctors at Great Ormond Street Hospital say the breakthrough was made possible by reprogramming her immune system […]

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Variation in numbers of people with CKD across Europe

Prevention / 21 September 2023

There is little information available that assesses whether the likelihood of acquiring CKD is the same in the different countries of Europe. The data below is taken from one study (Bruck et al, 2016). The numbers of people with CKD stages 1-5, varied from 3.3% of the population in Norway to 17.3% in northeast Germany.

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How many people with CKD3 go on to get CKD4-5?

Prevention / 21 September 2023

There is not much good research that enables us to answer this question. There is one study (Baek et al, 2012) that tells us something. The data below is taken from that study. 347 patients with stage 3 CKD were studied for ten years. They were enrolled between January 1997 and December 1999, and were

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How does diabetes damage the kidneys (5 ways)?

Causes / 21 September 2023

How does diabetes damage the kidneys (5 ways)? Kidney disease occurs in patients with both type 1 and type 2 diabetes mellitus, usually after at least 10 years of the disease. Diabetes can affect the kidneys in five ways: Diabetic nephropathy Renovascular disease Urinary tract infection Papillary necrosis Other kidney conditions. We will now go

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10 interesting facts about your kidneys

How the kidneys work / 20 September 2023

10 interesting facts about your kidneys Have you ever wondered where your kidneys actually are? Or if you can survive with just one kidney? Do you know what the hieroglyphic for wee is? Read this article to find out the answers and learn many more interesting and strange facts about the kidneys! 1. Your kidneys are

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Sick day rules – AKI prevention in CKD patients

Prevention / 19 September 2023

Sick day rules – AKI prevention in CKD patients If CKD patients become sick and dehydrated (usually secondary to an infection, e.g. urine, chest or gastrointestinal), they should be advised to withhold the 7 groups of medications below. This is because these drugs can precipitate AKI during such illnesses. And if they can be stopped

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Pros and cons of dialysis vs a kidney transplant

Dialysis and transplantation / 19 September 2023

Pros and cons of dialysis vs a kidney transplant In advanced CKD (CKD5; kidney failure) there are three options: dialysis, kidney transplantation, or supportive care (not having either). In this article we will describe the pros and cons of dialysis or a kidney transplant. It would seen obvious that a kidney transplant is ‘better’ than

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Pros and cons of haemodialysis vs peritoneal dialysis

Dialysis and transplantation / 18 September 2023

If you are not sure whether to choose haemodialysis or peritoneal dialysis, this article may be able to help you Let’s start with some basics. Whats is dialysis? Dialysis is an artificial method of filtering the blood to remove toxins, excess salts and water – in other words, the normal role of the kidneys. There

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CKDEx videos

Uncategorised / 18 September 2023

CKDEx videos A patients story – Darren, the Tiktok kidney warrior @ttkwarrior Question time with Doctor Andy Stein. Doctor Andy is a consultant Nephrologist at Coventry Hospital. #doctorandy #ttkwarrior #kidneydoctor #kidneyexpert #chronickidney #kidneyquestions ♬ original sound – Tiktok Kidney Warrior How the kidneys work Kidney physiology (health professionals) This is the science behind

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Immunosuppression and IgA nephropathy

Uncategorised / 18 September 2023

In a recent study Hao et al (CJASN, 2023) studied nearly 4000 Chinese patients with IgA nephropathy. Why does this matter? IgA nephropathy is the commonest type of glomerulonephritis, which is responsible for 10% of the patients on dialysis. The effects of immunosuppression (drugs to suppress the immune system) in the treatment of IgA nephropathy

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