Dr Andy Stein

New drug candidate shrinks kidney cysts in polycystic kidney disease (PKD)

New drug candidate shrinks kidney cysts in polycystic kidney disease (PKD) In a recent study on animals and cells by Fedeles, 2024, a compound originally developed as a cancer treatment, was shown to hold promise for patients with autosomal dominant polycystic kidney disease (ADPKD). The kidneys in PKD can become very big Why is this

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Chronic kidney disease: pathophysiology and progression

Chronic kidney disease: pathophysiology and progression This article is primarily for health professionals. Pathophysiology Unlike acute kidney injury (AKI), where the healing process is complete with complete functional kidney recovery, chronic and sustained insults from chronic and progressive nephropathies evolve to progressive kidney fibrosis and destruction of the normal architecture of the kidney. This affects

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