How do the kidneys work? (7 facts)
- Role. The kidney’s main role is to filter the blood
- Main function. This is because its main function is to remove waste products and extra water from the body
- Not one large filter
- Nephrons. Each kidney is made up of about a million tiny filtering units called nephrons (see above)
- Glomerulus/tubule. The nephron includes a filter, called the glomerulus, and a tubule. Each nephron filters a small amount of blood. The tubule is the drain out of the glomerulus, i.e. how the filtered blood gets out. The glomeruli are mainly in the cortex (outer area of the kidney) and tubules in the medulla (inner area)
- The glomerulus – is like a scrunched up tiny ball of blood vessels (called capillaries)
- The tubule – is a long U-shaped tube with three parts: proximal (means nearer to glomerulus) convoluted tubule (‘PCT’), Loop of Henle (‘loop’), and distal (further from glomerulus) convoluted tubule (‘DCT’)
- Two-step process. Nephrons work in two stages:
- Filtration – the glomerulus lets waste products and water pass through it; however, it prevents blood cells and large molecules, mostly proteins, from passing
- Reabsorption – the filtered fluid then passes through the tubule, where necessary minerals are absorbed back into the bloodstream
- Urine – is the final product which is passed into the bladder, and is removed from the body when you wee.
Other resources
The kidney has 6 other functions, as well as its main function (described above). They are described on CKDEx here:
- Functions of kidney 2: fluid balance (also affects blood pressure)
- Functions of kidney 3: acid-base balance
- Functions of kidney 4: blood pressure control (makes renin)
- Functions of kidney 5: anaemia, blood cells and EPO (makes erythropoietin)
- Functions of kidney 6: vitamin D activation (activates cholecalciferol)
- Functions of kidney 7: making prostaglandins.
This is a good video that explains how the kidneys work.
https://www.youtube.com/watch?v=hfKDA5kbL5o
Last Reviewed on 19 June 2024