What is bendroflumethiazide?

What is bendroflumethiazide?

  • Type of drug: thiazide diuretic
  • Use: fluid overload states (including CKD and nephrotic syndrome); hypertension
  • Dose: 2.5-10 mg once a day (5 mg is the standard dose)
  • Side-effects:
    • Dehydration – shown by dizziness and low blood pressure
    • Hyponatraemia, hypokalaemia and hypercalcaemia (low sodium and potassium levels; high calcium level) – that you will not normally notice
    • Gout – can cause (or worse) gout
  • Monitor: sodium, potassium and calcium levels.

Note 1. Other diuretics (e.g. Spironolactone and Amiloride) may give high potassium levels
Note 2. Mechanism of action = inhibits sodium (and therefore water) reabsorption at the beginning of the distal convoluted tubule (DCT).

Mechanism of action of different classes of diuretic at the level of... | Download Scientific Diagram

Other resources

CKD patient information (CKD Explained 30+ core articles)
Bendroflumethiazide (BNF)
10 best water tablets
Review article: Bell, 2022

Last Reviewed on 4 June 2024

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