Thursday 10th October 2024 marks World Mental Health Day and is a day us here at CKD Explained are keen to mark as Mental Health is something that resonates with a lot of us. It doesn’t matter if you are a patient, parent, relative, or friend;seeing someone who suffers from CKD can affect youremotional and […]
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Medical presentation of kidney disease (7 syndromes) This article is largely for health professionals. Key Points Kidney disease can present in 7 ways (ie. 7 different renal presentation syndromes): AKI or AKI on CKD CKD Proteinuria/nephrotic syndrome Micro/macrohaematuria Hypertension Nephritic syndrome Urological/transplant presentation. Note. Some patients present with 2 or or more of them –
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How many people have a rare kidney condition? In this article, we will describe how many people have a rare kidney condition. What makes a condition rare? There are different definitions of rare disease. Some experts think a disease is rare if it affects only a certain number of people out of every thousand, while
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Is CKD of unknown cause (CKDu) or Mesoamerican nephropathy (MeN) due to climate change? CKD of unknown cause (CKDu) or Mesoamerican nephropathy (MeN; also known as Mesoamerican endemic nephropathy), is a chronic kidney disease (CKD) that especially affects Central America and parts of Asia. It has also been reported in Africa, the Middle East and
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What is analgesic nephropathy? In this article we will describe what is analgesic nephropathy. It is a condition characterised by damage to the kidneys due to long-term or excessive use of certain pain medications; particularly analgesics like nonsteroidal anti-inflammatory drugs (NSAIDs) and combination analgesics containing phenacetin, aspirin, or acetaminophen. Note. NSAIDs can affect the kidneys
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What is IgG4-related disease (IgG4-RD)? Key points about IgG4-RD and kidneys. So. What is IgG4-related disease (IgG4-RD)? IgG4-related disease (IgG4-RD), a recently recognised systemic inflammatory disorder, generally presents as a mass-forming lesion, or lesions, or organ enlargement It is characterised by tissue infiltration with lymphocytes and IgG4-secreting plasma cells (IgG4+PC), various degrees of fibrosis (scarring)
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What are the 5 stages of diabetic nephropathy (and treatments)? There are 5 stages of diabetic nephropathy (DN). This is called the Mogensen classification of diabetic nephropathy. DN Stage 1. Hyperfiltration Years from diagnosis – at onset Urinary dipstick – negative uACR (lab urine test) – normal, i.e. < 3 mg/mmol GFR – increased (>150
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Gitelman Syndrome – overview Gitelman syndrome (GS) is an inherited (autosomal recessive) salt-losing kidney disease characterised by: Increased potassium loss in the urine Hypokalaemia and hypomagnesaemia = low potassium and magnesium (both electrolytes/minerals)in the blood Alkalosis = too much alkali in the blood Hypocalciuria = not enough calcium in the urine. The abnormality is in
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Retroperitoneal fibrosis (RPF) – overview Retroperitoneal fibrosis (RPF) is a rare condition in which there is fibrous tissue (scarring) in the retroperitoneal space, which is located behind the abdomen (tummy), in front of the spine. Here is an overview of retroperitoneal fibrosis. 1. Definition In retroperitoneal fibrosis the scar tissue in the retroperitoneum can compress
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What is medullary sponge kidney (MSK)? Medullary sponge kidney (MSK) is a congenital disorder, meaning it is present at birth. MSK occurs when small cysts (sacs) full of fluid form within the inner area (called the medulla) of the kidneys. It is also called Cacchi-Ricci Disease. In 70% of patients small stones form within the
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